Lymphangioleiomyomatosis(LAM)isararedisorderresultingfromproliferationinthelung,kidney,andaxiallymphaticsofabnormalsmoothmuscle–likecells(LAMcells)thatexhibitfeaturesofneoplasiaandneuralcrestorigin.Cysticdestructionofthelungwithprogressivepulmonarydysfunctionandthepresenceofabdominaltumors(eg,angiomyolipomas[AML],lymphangioleiomyomas)characterizethedisease.LAMtypicallyoccursinpremenopausalwomen,suggestingtheinvolvementoffemalehormonesindiseasepathogenesis.LAMcanoccurwithincreasedfrequencyinpatientswithtuberoussclerosis白癜风公益活动持续开展北京白癜风医院哪里好
